An innate twist between Crick's wobble and Watson-Crick base pairs

On the propeller structure of isolated Watson-Crick base pairs.

The nucleotide sequence dependence of the DNA and RNA secondary structure is a problem of current interest in molecular biophysics. The key role of stacking interactions in determining this dependence is widely accepted [1, 2], It is be­ lieved that the propeller twisting of base pairs, ob­ served in the structure of both nucleic acids and crystals of nucleosides and nucleotides is a direct man...

Molecular recognition of Watson-Crick-like purine-purine base pairs.

Nucleic acid duplexes containing non-Watson–Crick base pairs are of interest to several fields including structural biology, supramolecular chemistry, origin of life, and synthetic biology. An early observation of a natural non-Watson–Crick base pair was the tRNA–mRNA adenine–inosine wobble pair, and it is now known that purine–purine pairs occur frequently in natural RNAs, including ribosomes ...

Non-Watson-Crick base pairs in RNA-protein recognition.

The cellular functions of most RNA molecules involve protein binding, and non-Watson-Crick base pairs are hallmark sites for interactions with proteins. The determination of three-dimensional structures of RNA-peptide and RNA-protein complexes reveals the molecular basis of non-Watson-Crick base-pair recognition.

Relationship between Stacking and Hydrogen Bonding in Watson-crick Base Pairs

RNA folding: beyond Watson-Crick pairs.

Several crystal structures of RNA fragments, alone or in complex with a specific protein, have been recently solved. In addition, the structures of an artificial ribozyme, the leadzyme, and the cleavage product of a human pathogen ribozyme, have extended the structural diversity of ribozyme architectures. The attained set of folding rules and motifs expand the repertoire seen previously in tRNA...